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SLC7 family C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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SLC7 family members may be divided into two major groups: cationic amino acid transporters (CATs) and glycoprotein-associated amino acid transporters (gpaATs).

Cationic amino acid transporters are 14 TM proteins, which mediate pH- and sodium-independent transport of cationic amino acids (system y+), apparently as an exchange mechanism. These transporters are sensitive to inhibition by N-ethylmaleimide.


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CAT1 (High affinity cationic amino acid transporter 1 / SLC7A1) C Show summary »

CAT2 (Low affinity cationic amino acid transporter 2 / SLC7A2) C Show summary »

CAT3 (Cationic amino acid transporter 3 / SLC7A3) C Show summary »

CAT4 (Cationic amino acid transporter 4 / SLC7A4) Show summary »

Probable cationic amino acid transporter / SLC7A14 Show summary »

LAT1 (L-type amino acid transporter 1 / SLC7A5) C Show summary » More detailed page go icon to follow link

LAT2 (L-type amino acid transporter 2 / SLC7A8) C Show summary »

y+LAT1 (y+L amino acid transporter 1 / SLC7A7) C Show summary »

y+LAT2 (y+L amino acid transporter 2 / SLC7A6) C Show summary »

b0,+AT (b0,+-type amino acid transporter 1 / SLC7A9) C Show summary »

Asc-1 (Asc-type amino acid transporter 1 / SLC7A10) C Show summary »

xCT (Cystine/glutamate transporter / SLC7A11) C Show summary »

AGT1 / SLC7A13 C Show summary »

Target Id 903
Nomenclature AGT1
Systematic nomenclature SLC7A13
Previous and unofficial names AGT-1 | XAT2 | sodium-independent aspartate/glutamate transporter 1 | solute carrier family 7 (anionic amino acid transporter), member 13 | solute carrier family 7 member 13 | solute carrier family 7, (cationic amino acid transporter, y+ system) member 13 | solute carrier family 7
Genes SLC7A13 (Hs), Slc7a13 (Mm), Slc7a13 (Rn)
Ensembl ID ENSG00000164893 (Hs), ENSMUSG00000041052 (Mm), ENSRNOG00000024903 (Rn)
UniProtKB AC Q8TCU3 (Hs), Q91WN3 (Mm), Q5RKI7 (Rn)
Bioparadigms SLC Tables SLC7A13 (Hs)


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Further reading

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How to cite this family page

Database page citation (select format):

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters. Br J Pharmacol. 178 Suppl 1:S412-S513.