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Sodium-dependent HCO3- transporters C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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NBCe1 (Electrogenic sodium bicarbonate cotransporter 1 / SLC4A4) C Show summary »

Target Id 908
Nomenclature Electrogenic sodium bicarbonate cotransporter 1
Systematic nomenclature SLC4A4
Common abbreviation NBCe1
Previous and unofficial names kNBC1 | NBC2 | pNBC | Sodium bicarbonate cotransporter | hhNMC | HNBC1 | NBC1 | SLC4A5 | KNBC | Na+HCO3- cotransporter 4 | Nbc4 | solute carrier family 4 (anion exchanger), member 4 | solute carrier family 4 sodium bicarbonate cotransporter member 4 | NBC | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | solute carrier family 4 (anion exchanger)
Genes SLC4A4 (Hs), Slc4a4 (Mm), Slc4a4 (Rn)
Ensembl ID ENSG00000080493 (Hs), ENSMUSG00000060961 (Mm), ENSRNOG00000003134 (Rn)
UniProtKB AC Q9Y6R1 (Hs), O88343 (Mm), Q9JI66 (Rn)
Bioparadigms SLC Tables SLC4A4 (Hs)
Endogenous substrates
Stoichiometry 1 Na+ : 2/3 HCO3- (out) or 1 Na+ : CO32*

NBCe2 (Electrogenic sodium bicarbonate cotransporter 4 / SLC4A5) C Show summary »

NBCn1 (Electroneutral sodium bicarbonate cotransporter 1 / SLC4A7) C Show summary »

NBCn2 (Electroneutral sodium bicarbonate cotransporter 2 / SLC4A10) C Show summary »

NDCBE (NBCBE / SLC4A8) C Show summary »

BTR1 (NaBC1 / SLC4A11) C Show summary »

How to cite this family page

Database page citation:

Sodium-dependent HCO3- transporters. Accessed on 24/05/2024. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Transporters. Br J Pharmacol. 180 Suppl 2:S374-469.