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Sodium-dependent HCO3- transporters C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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NBCe1 (Electrogenic sodium bicarbonate cotransporter 1 / SLC4A4) C Show summary »

NBCe2 (Electrogenic sodium bicarbonate cotransporter 4 / SLC4A5) C Show summary »

Target Id 909
Nomenclature Electrogenic sodium bicarbonate cotransporter 4
Systematic nomenclature SLC4A5
Common abbreviation NBCe2
Previous and unofficial names NBC4 | electrogenic sodium bicarbonate cotransporter NBC4c | solute carrier family 4 member 5 | solute carrier family 4, sodium bicarbonate cotransporter, member 5 | solute carrier family 4 (sodium bicarbonate cotransporter), member 5 | solute carrier family 4
Genes SLC4A5 (Hs), Slc4a5 (Mm), Slc4a5 (Rn)
Ensembl ID ENSG00000188687 (Hs), ENSMUSG00000068323 (Mm), ENSRNOG00000010378 (Rn)
UniProtKB AC Q9BY07 (Hs), Q6RI88 (Rn)
Bioparadigms SLC Tables SLC4A5 (Hs)
Endogenous substrates
Stoichiometry 1 Na+ : 2/3 HCO3- (out) or 1 Na+ : CO32*

NBCn1 (Electroneutral sodium bicarbonate cotransporter 1 / SLC4A7) C Show summary »

NBCn2 (Electroneutral sodium bicarbonate cotransporter 2 / SLC4A10) C Show summary »

NDCBE (NBCBE / SLC4A8) C Show summary »

BTR1 (NaBC1 / SLC4A11) C Show summary »

How to cite this family page

Database page citation:

Sodium-dependent HCO3- transporters. Accessed on 24/09/2023. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters. Br J Pharmacol. 178 Suppl 1:S412-S513.