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Sodium-dependent HCO3- transporters C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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NBCe1 (Electrogenic sodium bicarbonate cotransporter 1 / SLC4A4) C Show summary »

NBCe2 (Electrogenic sodium bicarbonate cotransporter 4 / SLC4A5) C Show summary »

NBCn1 (Electroneutral sodium bicarbonate cotransporter 1 / SLC4A7) C Show summary »

NBCn2 (Electroneutral sodium bicarbonate cotransporter 2 / SLC4A10) C Show summary »

NDCBE (NBCBE / SLC4A8) C Show summary »

Target Id 912
Nomenclature NBCBE
Systematic nomenclature SLC4A8
Common abbreviation NDCBE
Previous and unofficial names Electroneutral Na+-driven Cl-HCO3 exchanger | k-NBC3 | NBC3 | electroneutral sodium bicarbonate exchanger 1 | Na-driven Cl-HCO3 exchanger NDCBE1-A | Na-driven Cl-HCO3 exchanger NDCBE1-B | Na-driven Cl-HCO3 exchanger NDCBE1-C | solute carrier family 4 (anion exchanger), member 8 | solute carrier family 4 member 8 | KNBC-3 | NDCBE | solute carrier family 4, sodium bicarbonate cotransporter, member 8 | solute carrier family 4 (anion exchanger)
Genes SLC4A8 (Hs), Slc4a8 (Mm), Slc4a8 (Rn)
Ensembl ID ENSG00000050438 (Hs), ENSMUSG00000023032 (Mm), ENSRNOG00000028879 (Rn)
UniProtKB AC Q2Y0W8 (Hs), Q8JZR6 (Mm), Q6RVG2 (Rn)
Bioparadigms SLC Tables SLC4A8 (Hs)
Endogenous substrates
Stoichiometry 1 Na+ : 2HCO3- (in) : 1 Cl- (out)

BTR1 (NaBC1 / SLC4A11) C Show summary »

How to cite this family page

Database page citation:

Sodium-dependent HCO3- transporters. Accessed on 24/09/2023. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters. Br J Pharmacol. 178 Suppl 1:S412-S513.