Top ▲

Vesicular glutamate transporters (VGLUTs) C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

Click here for help

« Hide

Vesicular glutamate transporters (VGLUTs) allow accumulation of glutamate into synaptic vesicles, as well as secretory vesicles in endocrine tissues. The roles of VGLUTs in kidney and liver are unclear. These transporters appear to utilize the proton gradient and also express a chloride conductance [1].

Transporters

1007
Click here for help

VGLUT1 (Vesicular glutamate transporter 1 / SLC17A7) C Show summary »


Target Id 1007
Nomenclature Vesicular glutamate transporter 1
Systematic nomenclature SLC17A7
Common abbreviation VGLUT1
Previous and unofficial names BNPI | brain-specific Na-dependent inorganic phosphate cotransporter | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 | solute carrier family 17 (vesicular glutamate transporter), member 7 | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter)
Genes SLC17A7 (Hs), Slc17a7 (Mm), Slc17a7 (Rn)
Ensembl ID ENSG00000104888 (Hs), ENSMUSG00000070570 (Mm), ENSRNOG00000020650 (Rn)
UniProtKB AC Q9P2U7 (Hs), Q3TXX4 (Mm), Q62634 (Rn)
Bioparadigms SLC Tables SLC17A7 (Hs)
Endogenous substrates L-glutamic acid > D-glutamic acid
Stoichiometry Unknown

VGLUT2 (Vesicular glutamate transporter 2 / SLC17A6) C Show summary »

VGLUT3 (Vesicular glutamate transporter 3 / SLC17A8) C Show summary »

Comments

Click here for help

Show »

References

Click here for help

Show »

How to cite this family page

Database page citation:

Vesicular glutamate transporters (VGLUTs). Accessed on 06/12/2021. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=191.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Transporters. Br J Pharmacol. 176 Issue S1: S397-S493.