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SLC47 family of multidrug and toxin extrusion transporters C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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These proton:organic cation exchangers are predicted to have 13 TM segments [11] and are suggested to be responsible for excretion of many drugs in the liver and kidneys [1].

Transporters

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MATE1 (Multidrug and toxin extrusion / SLC47A1) C Show summary »

MATE2-K (MATE2 / SLC47A2) C Show summary »

Comments

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Further reading

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References

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NC-IUPHAR subcommittee and family contributors

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How to cite this family page

Database page citation (select format):

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters. Br J Pharmacol. 178 Suppl 1:S412-S513.