Dimethylarginine dimethylaminohydrolases | Enzymes | IUPHAR/BPS Guide to PHARMACOLOGY

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L-Arginine turnover
Dimethylarginine dimethylaminohydrolases

Dimethylarginine dimethylaminohydrolases C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Dimethylarginine dimethylaminohydrolases (DDAH, EC 3.5.3.18) are cytoplasmic enzymes which hydrolyse N^G,N^G-dimethyl-L-arginine to form dimethylamine and L-citrulline.

Enzymes

DDAH1 (N^G,N^G-Dimethylarginine dimethylaminohydrolase 1) C Show summary »« Hide summary

DDAH2 (N^G,N^G-Dimethylarginine dimethylaminohydrolase 2) C Show summary »« Hide summary

Target Id

1248

Nomenclature

N^G,N^G-Dimethylarginine dimethylaminohydrolase 2

Common abbreviation

DDAH2

Previous and unofficial names

DDAHII | dimethylargininase-2 | S-phase protein | G6a | NG30

Genes

DDAH2 (Hs), Ddah2 (Mm), Ddah2 (Rn)

Ensembl ID

ENSG00000213722 (Hs), ENSMUSG00000007039 (Mm), ENSRNOG00000000842 (Rn)

UniProtKB AC

O95865 (Hs), Q99LD8 (Mm), Q6MG60 (Rn)

EC number

3.5.3.18

References

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How to cite this family page

Database page citation:

Dimethylarginine dimethylaminohydrolases. Accessed on 08/06/2023. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=252.

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes. Br J Pharmacol. 178 Suppl 1:S313-S411.