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CYP1 family C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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CYP1 enzymes catalyse the generation of highly mutagenic compounds via activation of procarcinogens (such as polycyclic aromatic hydrocarbons and aromatic amines) that are present in combustion products. They can also deactivate many anticancer agents [4].

Enzymes

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CYP1A1 C Show summary » More detailed page go icon to follow link

CYP1A2 C Show summary » More detailed page go icon to follow link

CYP1B1 C Show summary » More detailed page go icon to follow link

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References

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How to cite this family page

Database page citation (select format):

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Enzymes. Br J Pharmacol. 176 Issue S1: S297-S396.