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CYP4 family C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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CYP4 family enzymes catalyse the ω-oxidation of endogenous fatty acids and eicosanoids [4]. They have been proposed as molecular targets for the treatment of fatty acid-linked orphan diseases.

Enzymes

1346
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CYP4A11 C Show summary »

CYP4A22 C Show summary »

CYP4B1 C Show summary »

CYP4F2 C Show summary »

CYP4F3 C Show summary »

CYP4F8 C Show summary »


Target Id 1346
Nomenclature CYP4F8
Previous and unofficial names cytochrome P450, subfamily IVF, polypeptide 8 | cytochrome P450, family 4, subfamily F, polypeptide 8
Genes CYP4F8 (Hs)
Ensembl ID ENSG00000186526 (Hs)
UniProtKB AC P98187 (Hs)
EC number
1.14.14.1
Comment Converts PGH2 to 19-hydroxyPGH2 [1] and 8,9-EET or 11,12-EET to 18-hydroxy-8,9-EET or 18-hydroxy-11,12-EET [13].

CYP4F11 C Show summary »

CYP4F12 C Show summary »

CYP4F22 C Show summary »

CYP4V2 C Show summary »

CYP4X1 C Show summary »

CYP4Z1 C Show summary »

References

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How to cite this family page

Database page citation (select format):

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes. Br J Pharmacol. 178 Suppl 1:S313-S411.