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CYP4 family C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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CYP4 family enzymes catalyse the ω-oxidation of endogenous fatty acids and eicosanoids [4]. They have been proposed as molecular targets for the treatment of fatty acid-linked orphan diseases.

Enzymes

1350
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CYP4A11 C Show summary »

CYP4A22 C Show summary »

CYP4B1 C Show summary »

CYP4F2 C Show summary »

CYP4F3 C Show summary »

CYP4F8 C Show summary »

CYP4F11 C Show summary »

CYP4F12 C Show summary »

CYP4F22 C Show summary »

CYP4V2 C Show summary »


Target Id 1350
Nomenclature CYP4V2
Previous and unofficial names cytochrome P450 4V2 | cytochrome P450, family 4, subfamily V, polypeptide 2
Genes CYP4V2 (Hs)
Ensembl ID ENSG00000145476 (Hs)
UniProtKB AC Q6ZWL3 (Hs)
EC number
1.14.14.79
Comment Converts myristic acid to 14-hydroxymyristic acid [12]. Variants are associated with ocular disease [18].

CYP4X1 C Show summary »

CYP4Z1 C Show summary »

References

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How to cite this family page

Database page citation (select format):

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Enzymes. Br J Pharmacol. 176 Issue S1: S297-S396.