MKN subfamily

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Targets
Enzymes
Kinases (EC 2.7.x.x)
CAMK: Calcium/calmodulin-dependent protein kinases
MAPK-Activated Protein Kinase (MAPKAPK) family
MKN subfamily

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Enzymes

Mnk1 (MAPK interacting serine/threonine kinase 1) Show summary »« Hide summary More detailed page go icon to follow link

Target Id

2104

Nomenclature

MAPK interacting serine/threonine kinase 1

Common abbreviation

Mnk1

Previous and unofficial names

MAP kinase signal-integrating kinase 1 | MAP kinase interacting serine/threonine kinase 1 | MAP kinase-interacting serine/threonine kinase 1

Genes

MKNK1 (Hs), Mknk1 (Mm), Mknk1 (Rn)

Ensembl ID

ENSG00000079277 (Hs), ENSMUSG00000028708 (Mm), ENSRNOG00000010381 (Rn)

UniProtKB AC

Q9BUB5 (Hs), O08605 (Mm), Q4G050 (Rn)

EC number

2.7.11.1

Mnk2 (MAPK interacting serine/threonine kinase 2) Show summary »« Hide summary More detailed page go icon to follow link

Target Id

2105

Nomenclature

MAPK interacting serine/threonine kinase 2

Common abbreviation

Mnk2

Previous and unofficial names

MAP kinase-interacting serine/threonine kinase 2 | G protein-coupled receptor kinase 7 | MAP kinase interacting serine/threonine kinase 2 | MAP kinase signal-integrating kinase 2

Genes

MKNK2 (Hs), Mknk2 (Mm), Mknk2 (Rn)

Ensembl ID

ENSG00000099875 (Hs), ENSMUSG00000020190 (Mm), ENSRNOG00000029028 (Rn)

UniProtKB AC

Q9HBH9 (Hs), Q8CDB0 (Mm), Q5U2N4 (Rn)

EC number

2.7.11.1

How to cite this family page

Database page citation:

MKN subfamily. Accessed on 13/08/2026. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=513.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Gibb AJ, Kelly E, Mathie AA, Peach CJ, Veale EL, Armstrong JF, Faccenda E, Harding SD, Southan C, Davies JA et al. (2025) The Concise Guide to PHARMACOLOGY 2025/26: Enzymes. Br J Pharmacol. 182: S307-S403.