S10: Carboxypeptidase Y

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Enzymes

Cathepsin A Show summary »« Hide summary More detailed page

Serine carboxypeptidase 1 Show summary »« Hide summary

Vitellogenic carboxypeptidase-like protein Show summary »« Hide summary

Target Id

1583

Nomenclature

Vitellogenic carboxypeptidase-like protein

Previous and unofficial names

carboxypeptidase WUG | CP-Mac carboxypeptidase | vitellogenic carboxypeptidase-like protein | VCP-like protein | carboxypeptidase

Genes

CPVL (Hs), Cpvl (Mm), Cpvl (Rn)

Ensembl ID

ENSG00000106066 (Hs), ENSMUSG00000052955 (Mm), ENSRNOG00000009172 (Rn)

UniProtKB AC

Q9H3G5 (Hs), Q9D3S9 (Mm), Q4QR71 (Rn)

EC number

3.4.16.-

References

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1. Ruf S et al.. (2013) Use of boceprevir and related compounds in atherosclerosis, heart failure, renal diseases, liver diseases or inflammatory diseases. Patent number: WO2013072327. Assignee: Sanofi. Priority date: 14/11/2011. Publication date: 23/05/2013.

2. Ruf S et al. (2013) Use of telaprevir and related compounds in atherosclerosis, heart failure, renal diseases, liver diseases or inflammatory diseases. Patent number: WO2013072328. Assignee: Sanofi. Priority date: 14/11/2011. Publication date: 23/05/2013.

3. Ruf S et al. (2014) Biaryl-propionic acid derivatives and their use as pharmaceuticals. Patent number: WO2014154727. Assignee: Sanofi. Priority date: 20/03/2013. Publication date: 02/10/2014.

4. Ruf S, Buning C, Schreuder H, Horstick G, Linz W, Olpp T, Pernerstorfer J, Hiss K, Kroll K, Kannt A et al.. (2012) Novel β-amino acid derivatives as inhibitors of cathepsin A. J. Med. Chem., 55 (17): 7636-49. [PMID:22861813]

How to cite this family page

Database page citation:

S10: Carboxypeptidase Y. Accessed on 22/02/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=756.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2017) The Concise Guide to PHARMACOLOGY 2017/18: Enzymes. Br J Pharmacol. 174 Suppl 1: S272-S359.