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Neutral sphingomyelinase coupling factors C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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Protein FAN [1] and polycomb protein EED [3] allow coupling between TNF receptors and neutral sphingomyelinase phosphodiesterases.


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embryonic ectoderm development C Show summary » More detailed page go icon to follow link

neutral sphingomyelinase activation associated factor C Show summary »

Target Id 2495
Nomenclature neutral sphingomyelinase activation associated factor
Previous and unofficial names Factor associated with neutral sphingomyelinase activation | FAN | neutral sphingomyelinase (N-SMase) activation associated factor
Genes NSMAF (Hs), Nsmaf (Mm), Nsmaf (Rn)
Ensembl ID ENSG00000035681 (Hs), ENSMUSG00000028245 (Mm), ENSRNOG00000010234 (Rn)
UniProtKB AC Q92636 (Hs), O35242 (Mm)


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How to cite this family page

Database page citation (select format):

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.