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SLC52 family of riboflavin transporters C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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Riboflavin, also known as vitamin B2, is a precursor of the enzyme cofactors flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). Riboflavin transporters are predicted to possess 10 or 11 TM segments.


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RFVT1 (solute carrier family 52 member 1 / SLC52A1) C Show summary »

RFVT2 (solute carrier family 52 member 2 / SLC52A2) C Show summary »

RFVT3 (solute carrier family 52 member 3 / SLC52A3) C Show summary »

Target Id 2573
Nomenclature solute carrier family 52 member 3
Systematic nomenclature SLC52A3
Common abbreviation RFVT3
Previous and unofficial names RFT2 | RFVT3 | Riboflavin transporter 2 | solute carrier family 52 (riboflavin transporter), member 3 | solute carrier protein family 52, member 3 | solute carrier protein family 52
Genes SLC52A3 (Hs), Slc52a3 (Mm), Slc52a3 (Rn)
Ensembl ID ENSG00000101276 (Hs), ENSMUSG00000027463 (Mm), ENSRNOG00000005132 (Rn)
UniProtKB AC Q9NQ40 (Hs), Q9D6X5 (Mm), Q4FZU9 (Rn)
Bioparadigms SLC Tables SLC52A3 (Hs)
Endogenous substrates
riboflavin pKm 3.5 [1]
Stoichiometry H+-dependent


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Further reading

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How to cite this family page

Database page citation:

SLC52 family of riboflavin transporters. Accessed on 22/09/2023. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters. Br J Pharmacol. 178 Suppl 1:S412-S513.