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G-alpha family G(q) subfamily

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Enzymes

2914
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G protein subunit alpha q Show summary »

Target Id 2914
Nomenclature G protein subunit alpha q
Previous and unofficial names Guanine nucleotide-binding protein G(q) subunit alpha | guanine nucleotide binding protein (G protein), q polypeptide | G-alpha-q | Gαq | guanine nucleotide binding protein, alpha q polypeptide | guanine nucleotide binding protein
Genes GNAQ (Hs), Gnaq (Mm), Gnaq (Rn)
Ensembl ID ENSG00000156052 (Hs), ENSMUSG00000024639 (Mm), ENSRNOG00000063937 (Rn)
UniProtKB AC P50148 (Hs), P21279 (Mm), P82471 (Rn)
Selective inhibitors
FR900359 pIC50 7.5 [1] - Hamster
YM-254890 pIC50 7.0 [1] - Hamster

References

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How to cite this family page

Database page citation:

G-alpha family G(q) subfamily. Accessed on 06/04/2026. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=935.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Gibb AJ, Kelly E, Mathie AA, Peach CJ, Veale EL, Armstrong JF, Faccenda E, Harding SD, Southan C, Davies JA et al. (2025) The Concise Guide to PHARMACOLOGY 2025/26: Enzymes. Br J Pharmacol. 182: S307-S403.