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Protein tyrosine phosphatases non-receptor type (PTPN)

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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Protein tyrosine phosphatases (PTPs) catalyse the hydrolysis of phosphate monoesters on tyrosine residues, in opposition to tyrosine kinase-catalysed phosphorylation.
The HGNC lists 17 members in the 'Protein tyrosine phosphatases, non-receptor type (PTPN)' family (ID 812).


PTP1B (protein tyrosine phosphatase non-receptor type 1) Show summary » More detailed page

LYP (protein tyrosine phosphatase non-receptor type 22 / PTPN22) Show summary » More detailed page


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How to cite this family page

Database page citation:

Protein tyrosine phosphatases non-receptor type (PTPN). Accessed on 01/10/2020. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Enzymes. Br J Pharmacol. 176 Issue S1: S297-S396.