RIPK3 inhibitor 18 [Ligand Id: 10389] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| MET proto-oncogene, receptor tyrosine kinase in Human [GtoPdb: 1815] [UniProtKB: P08581] | ||||||||
| GtoPdb | - | - | 5.96 | pIC50 | 1100 | nM | IC50 | ACS Med Chem Lett (2019) : |
| EPH receptor A5 in Human [GtoPdb: 1825] [UniProtKB: P54756] | ||||||||
| GtoPdb | - | - | 7.85 | pIC50 | 14 | nM | IC50 | ACS Med Chem Lett (2019) : |
| EPH receptor A8 in Human [GtoPdb: 1828] [UniProtKB: P29322] | ||||||||
| GtoPdb | - | - | 7.59 | pIC50 | 26 | nM | IC50 | ACS Med Chem Lett (2019) : |
| EPH receptor B2 in Human [GtoPdb: 1831] [UniProtKB: P29323] | ||||||||
| GtoPdb | - | - | 8 | pIC50 | 10 | nM | IC50 | ACS Med Chem Lett (2019) : |
| discoidin domain receptor tyrosine kinase 2 in Human [GtoPdb: 1844] [UniProtKB: Q16832] | ||||||||
| GtoPdb | - | - | 7.96 | pIC50 | 11 | nM | IC50 | ACS Med Chem Lett (2019) : |
| FGR proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2024] [UniProtKB: P09769] | ||||||||
| GtoPdb | - | - | 7.92 | pIC50 | 12 | nM | IC50 | ACS Med Chem Lett (2019) : |
| mitogen-activated protein kinase kinase kinase kinase 3 in Human [GtoPdb: 2087] [UniProtKB: Q8IVH8] | ||||||||
| GtoPdb | - | - | 7.92 | pIC50 | 12 | nM | IC50 | ACS Med Chem Lett (2019) : |
| Raf-1 proto-oncogene, serine/threonine kinase in Human [GtoPdb: 2184] [UniProtKB: P04049] | ||||||||
| GtoPdb | - | - | 7.96 | pIC50 | 11 | nM | IC50 | ACS Med Chem Lett (2019) : |
| receptor interacting serine/threonine kinase 1 in Human [GtoPdb: 2189] [UniProtKB: Q13546] | ||||||||
| GtoPdb | - | - | 5.26 | pIC50 | 5500 | nM | IC50 | ACS Med Chem Lett (2019) : |
| receptor interacting serine/threonine kinase 3 in Human [GtoPdb: 2191] [UniProtKB: Q9Y572] | ||||||||
| GtoPdb | - | - | 8.04 | pIC50 | 9.1 | nM | IC50 | ACS Med Chem Lett (2019) : |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
