compound 9 [Kumar et al., 2019] [Ligand Id: 10448] activity data from GtoPdb

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  • COX-1 in Sheep [GtoPdb: 1375]
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  • COX-2 in Human [GtoPdb: 1376] [UniProtKB: P35354]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
COX-1 in Sheep [GtoPdb: 1375]
GtoPdb Inhibition of ovine COX1 using a proprietary COX inhibitor screening assay kit (Cayman chemical company). - 4.4 pIC50 39920 nM IC50 Eur J Med Chem (2019) 182: 111601 [PMID:31445233]
COX-2 in Human [GtoPdb: 1376] [UniProtKB: P35354]
GtoPdb Inhibition of recombinant hCOX2 in vitro. - 6.44 pIC50 367 nM IC50 Eur J Med Chem (2019) 182: 111601 [PMID:31445233]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.