compound 39 [PMID: 31742400] [Ligand Id: 10585] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| CCR2 in Human [GtoPdb: 59] [UniProtKB: P41597] | ||||||||
| GtoPdb | Binding affinity determined from a radioligand binding assay, measuring displacement of [3H]-CCR2-RA-[R] from U2OS cells stably expressing human CCR2. | - | 8.8 | pKi | 1.6 | nM | Ki | J Med Chem (2019) 62: 11035-11053 [PMID:31742400] |
| CCR5 in Human [GtoPdb: 62] [UniProtKB: P51681] | ||||||||
| GtoPdb | Antagonist effect on CCL3-induced β-arrestin recruitment in U2OS cells stably expressing human CCR5. | - | 7.08 | pIC50 | 84 | nM | IC50 | J Med Chem (2019) 62: 11035-11053 [PMID:31742400] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
