ChEMBL ligand: CHEMBL1938400 (Pf-03715455, Pf-3715455)
misshapen like kinase 1/Misshapen-like kinase 1 in Human [ChEMBL: CHEMBL5518] [GtoPdb: 2103] [UniProtKB: Q8N4C8] There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase 11/Mitogen-activated protein kinase 11 in Human [ChEMBL: CHEMBL3961] [GtoPdb: 1500] [UniProtKB: Q15759] There should be some charts here, you may need to enable JavaScript!
fms related receptor tyrosine kinase 1/Vascular endothelial growth factor receptor 1 in Human [ChEMBL: CHEMBL1868] [GtoPdb: 1812] [UniProtKB: P17948] There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase 14 in Human [GtoPdb: 1499] [UniProtKB: Q16539] There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase 13 in Human [GtoPdb: 1502] [UniProtKB: O15264] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
misshapen like kinase 1/Misshapen-like kinase 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5518] [GtoPdb: 2103] [UniProtKB: Q8N4C8]
GtoPdb	-	-	8.22	pIC50	6	nM	IC50	J Med Chem (2011) 54: 7797-814 [PMID:21888439]
ChEMBL	Inhibition of MINK	B	8.22	pIC50	6	nM	IC50	J Med Chem (2011) 54: 7797-7814 [PMID:21888439]
mitogen-activated protein kinase 11/Mitogen-activated protein kinase 11 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3961] [GtoPdb: 1500] [UniProtKB: Q15759]
ChEMBL	Inhibition of p38beta MAPK	B	7.64	pIC50	23	nM	IC50	J Med Chem (2011) 54: 7797-7814 [PMID:21888439]
fms related receptor tyrosine kinase 1/Vascular endothelial growth factor receptor 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1868] [GtoPdb: 1812] [UniProtKB: P17948]
ChEMBL	Inhibition of human VEGFR1	B	6.05	pIC50	890	nM	IC50	J Med Chem (2011) 54: 7797-7814 [PMID:21888439]
mitogen-activated protein kinase 14 in Human [GtoPdb: 1499] [UniProtKB: Q16539]
GtoPdb	-	-	12	pKd	0	nM	Kd	J Med Chem (2011) 54: 7797-814 [PMID:21888439]
GtoPdb	-	-	9.06	pIC50	0.88	nM	IC50	J Med Chem (2011) 54: 7797-814 [PMID:21888439]
mitogen-activated protein kinase 13 in Human [GtoPdb: 1502] [UniProtKB: O15264]
GtoPdb	-	-	7.64	pIC50	23	nM	IC50	J Med Chem (2011) 54: 7797-814 [PMID:21888439]

ChEMBL data shown on this page come from version 36:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]