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Ligand: trimipramine
Comments: tricyclic antidepressant (TCA) with antidepressant, anxiolytic, antipsychotic and sedative effects. Trimipramine is a racemic compound
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Ligand: agomelatine
Comments: antidepressant, devoid of the side-effects caused by SSRI, SNRI and tricyclic antidepressants. The drug
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Ligand: protriptyline
Mechanism of action: Tricyclic antidepressants inhibit reuptake of serotonin and norepinephrine by their respective transporters, SERT (SLC6A4) and NET (SLC6A2
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Ligand: doxepin
Clinical use: tricyclic antidepressant used in the treatment of major depressive disorder and anxiety. The drug's positive
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Ligand: amitriptyline
Comments: Amitriptyline is a tricyclic antidepressant (TCA).
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Ligand: opipramol
Comments: tricyclic antidepressant (TCA) . It acts primarily as a sigma (sigma) receptor agonist. Weak antiviral activity
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Ligand: desipramine
Comments: Desipramine is one of the tricyclic antidepressants.
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Ligand: tianeptine
Comments: tricyclic antidepressant (TCA), but evidence suggests that it has a quite different pharmacological mechanism of action
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Ligand: dosulepin
Comments: tricyclic antidepressant. Functionally it acts as a serotonin-norepinephrine reuptake inhibitor (SNRI) with anticholinergic, antihistamine
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Ligand: cyclobenzaprine
Comments: tricyclic antidepressant similar to . It acts as a skeletal muscle relaxant and central nervous system
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