Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	396	5q32	STK32A	serine/threonine kinase 32A
Mouse	-	398	18 B3	Stk32a	serine/threonine kinase 32A
Rat	-	397	18p11	Stk32a	serine/threonine kinase 32A

Database Links
Alphafold	Q8WU08 (Hs), Q8BGW6 (Mm)
BRENDA	2.7.11.1
ChEMBL Target	CHEMBL6150 (Hs)
Ensembl Gene	ENSG00000169302 (Hs), ENSMUSG00000039954 (Mm), ENSRNOG00000027066 (Rn)
Entrez Gene	202374 (Hs), 269019 (Mm), 364858 (Rn)
Human Protein Atlas	ENSG00000169302 (Hs)
KEGG Enzyme	2.7.11.1
KEGG Gene	hsa:202374 (Hs), mmu:269019 (Mm), rno:364858 (Rn)
Pharos	Q8WU08 (Hs)
RefSeq Nucleotide	NM_001112724 (Hs), NM_178749 (Mm), NM_001191894 (Rn)
RefSeq Protein	NP_001106195 (Hs), NP_848864 (Mm), NP_001178823 (Rn)
UniProtKB	Q8WU08 (Hs), Q8BGW6 (Mm)
Wikipedia	STK32A (Hs)

Selected 3D Structures
	Description:  Crystal structure of human serine/threonine-protein kinase 32A (YANK1). PDB Id:  4FR4 Resolution:  2.29Å Species:  Human References:

Enzyme Reaction
EC Number: 2.7.11.1

DiscoveRx KINOMEscan® screen
A screen of 72 inhibitors against 456 human kinases. Quantitative data were derived using DiscoveRx KINOMEscan® platform. http://www.discoverx.com/services/drug-discovery-development-services/kinase-profiling/kinomescan Reference: 1-2
Key to terms and symbols		Click column headers to sort
Target used in screen: YANK1
Ligand Sp. Type Action Value Parameter staurosporine Hs Inhibitor Inhibition 7.9 pKd NVP-TAE684 Hs Inhibitor Inhibition 7.9 pKd linifanib Hs Inhibitor Inhibition 6.2 pKd PP-242 Hs Inhibitor Inhibition 6.2 pKd SB203580 Hs Inhibitor Inhibition 5.9 pKd bosutinib Hs Inhibitor Inhibition 5.7 pKd lestaurtinib Hs Inhibitor Inhibition 5.7 pKd tamatinib Hs Inhibitor Inhibition 5.6 pKd midostaurin Hs Inhibitor Inhibition 5.6 pKd PD-173955 Hs Inhibitor Inhibition 5.6 pKd
Displaying the top 10 most potent ligands  View all ligands in screen »