Aminopeptidase A | M18: Aminopeptidase I | IUPHAR/BPS Guide to PHARMACOLOGY

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Aminopeptidase A

Target not currently curated in GtoImmuPdb

Target id: 1559

Nomenclature: Aminopeptidase A

Family: M18: Aminopeptidase I

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 485 2q36.1 DNPEP aspartyl aminopeptidase
Mouse - 475 1 C3-C4 Dnpep aspartyl aminopeptidase
Rat - 475 9q33 Dnpep aspartyl aminopeptidase
Previous and Unofficial Names
ASPEP | DAP | cytosolic aminopeptidase
Database Links
Specialist databases
MEROPS M18.002 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction
EC Number:

Download all structure-activity data for this target as a CSV file

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
compound 9 [PMID: 1738140] Hs Inhibition 6.3 pKi 1
pKi 6.3 (Ki 5.1x10-7 M) [1]
Inhibitor Comments
As the source of the enzyme used to generate the Ki value for compound 9 is not clear from the referenced article, we have not specified species in the table above.


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1. Ocain TD, Rich DH. (1992) alpha-Keto amide inhibitors of aminopeptidases. J. Med. Chem., 35 (3): 451-6. [PMID:1738140]

How to cite this page

M18: Aminopeptidase I: Aminopeptidase A. Last modified on 29/07/2015. Accessed on 14/08/2020. IUPHAR/BPS Guide to PHARMACOLOGY,