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Gene and Protein Information ![]() |
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Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | - | 443 | 12q15 | CPM | carboxypeptidase M | |
Mouse | - | 443 | 10 D2 | Cpm | carboxypeptidase M | |
Rat | - | 443 | 7q22 | Cpm | carboxypeptidase M |
Previous and Unofficial Names ![]() |
renal carboxypeptidase | urinary carboxypeptidase B |
Database Links ![]() |
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Specialist databases | |
MEROPS | M14.006 (Hs) |
Other databases | |
Alphafold | P14384 (Hs), Q80V42 (Mm), D4A9Q5 (Rn) |
BRENDA | 3.4.17.12 |
ChEMBL Target | CHEMBL3038 (Hs) |
Ensembl Gene | ENSG00000135678 (Hs), ENSMUSG00000020183 (Mm), ENSRNOG00000066159 (Rn) |
Entrez Gene | 1368 (Hs), 70574 (Mm), 314855 (Rn) |
Human Protein Atlas | ENSG00000135678 (Hs) |
KEGG Enzyme | 3.4.17.12 |
KEGG Gene | hsa:1368 (Hs), mmu:70574 (Mm), rno:314855 (Rn) |
OMIM | 114860 (Hs) |
Pharos | P14384 (Hs) |
RefSeq Nucleotide | NM_001005502 (Hs), NM_001874 (Hs), NM_198320 (Hs), NM_027468 (Mm), NM_001108098 (Rn) |
RefSeq Protein | NP_938079 (Hs), NP_001005502 (Hs), NP_001865 (Hs), NP_081744 (Mm), NP_001101568 (Rn) |
UniProtKB | P14384 (Hs), Q80V42 (Mm), D4A9Q5 (Rn) |
Wikipedia | CPM (Hs) |
Enzyme Reaction ![]() |
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Download all structure-activity data for this target as a CSV file
Inhibitors | |||||||||||||||||||||||||||||||||||||||||||||||||||
Key to terms and symbols | View all chemical structures | Click column headers to sort | |||||||||||||||||||||||||||||||||||||||||||||||||
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Immunopharmacology Comments |
Possible role in immune system discussed in [2]. |
1. Barrow JC, Nantermet PG, Stauffer SR, Ngo PL, Steinbeiser MA, Mao SS, Carroll SS, Bailey C, Colussi D, Bosserman M et al.. (2003) Synthesis and evaluation of imidazole acetic acid inhibitors of activated thrombin-activatable fibrinolysis inhibitor as novel antithrombotics. J Med Chem, 46 (25): 5294-7. [PMID:14640538]
2. Deiteren K, Hendriks D, Scharpé S, Lambeir AM. (2009) Carboxypeptidase M: Multiple alliances and unknown partners. Clin Chim Acta, 399 (1-2): 24-39. [PMID:18957287]
M14: Carboxypeptidase A: Carboxypeptidase M. Last modified on 25/07/2016. Accessed on 12/02/2025. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1596.