Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	483	11q22.2	MMP20	matrix metallopeptidase 20
Mouse	-	482	9 A1	Mmp20	matrix metallopeptidase 20 (enamelysin)
Rat	-	482	8q11	Mmp20	matrix metallopeptidase 20

Previous and Unofficial Names

enamel metalloproteinase

Database Links
Specialist databases
MEROPS	M10.019 (Hs)
Other databases
Alphafold	O60882 (Hs), P57748 (Mm)
BRENDA	3.4.24.-
CATH/Gene3D	2.110.10.10, 3.40.390.10
ChEMBL Target	CHEMBL1938226 (Hs)
DrugBank Target	O60882 (Hs)
Ensembl Gene	ENSG00000137674 (Hs), ENSMUSG00000018620 (Mm), ENSRNOG00000021896 (Rn)
Entrez Gene	9313 (Hs), 30800 (Mm), 300341 (Rn)
Human Protein Atlas	ENSG00000137674 (Hs)
KEGG Enzyme	3.4.24.-
KEGG Gene	hsa:9313 (Hs), mmu:30800 (Mm), rno:300341 (Rn)
OMIM	604629 (Hs)
Orphanet	ORPHA139176 (Hs)
Pharos	O60882 (Hs)
RefSeq Nucleotide	NM_004771 (Hs), NM_013903 (Mm), NM_001106800 (Rn)
RefSeq Protein	NP_004762 (Hs), NP_038931 (Mm), NP_001100270 (Rn)
UniProtKB	O60882 (Hs), P57748 (Mm)
Wikipedia	MMP20 (Hs)

Enzyme Reaction
EC Number: 3.4.24.-

Clinically-Relevant Mutations and Pathophysiology
Disease:  Amelogenesis imperfecta, hypomaturation type, IIA2; AI2A2 Synonyms: Amelogenesis imperfecta [Disease Ontology: DOID:2187] Hypomaturation amelogenesis imperfecta [Orphanet: ORPHA100033] Disease Ontology: DOID:2187 OMIM: 612529 Orphanet: ORPHA100033