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MMP26

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Target not currently curated in GtoImmuPdb

Target id: 1648

Nomenclature: MMP26

Family: M10: Matrix metallopeptidase

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 261 11p15.4 MMP26 matrix metallopeptidase 26
Previous and Unofficial Names Click here for help
endometase | matrilysin 2
Database Links Click here for help
Specialist databases
MEROPS M10.029 (Hs)
Other databases
Alphafold
BRENDA
CATH/Gene3D
ChEMBL Target
DrugBank Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
Pharos
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction Click here for help
EC Number: 3.4.24.-

Download all structure-activity data for this target as a CSV file go icon to follow link

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
ilomastat Small molecule or natural product Click here for species-specific activity table Ligand has a PDB structure Hs Inhibition 7.8 pIC50 1
pIC50 7.8 (IC50 1.7x10-8 M) [1]
Immuno Process Associations
Immuno Process:  Inflammation
Immuno Process:  Immune regulation

References

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1. Ma D, Wu W, Yang G, Li J, Li J, Ye Q. (2004) Tetrahydroisoquinoline based sulfonamide hydroxamates as potent matrix metalloproteinase inhibitors. Bioorg Med Chem Lett, 14 (1): 47-50. [PMID:14684295]

How to cite this page

M10: Matrix metallopeptidase: MMP26. Last modified on 16/03/2017. Accessed on 07/12/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1648.