NLRP4 | NOD-like receptor family | IUPHAR/BPS Guide to PHARMACOLOGY

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Target not currently curated in GtoImmuPdb

Target id: 1771

Nomenclature: NLRP4

Family: NOD-like receptor family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 994 19q13.43 NLRP4 NLR family pyrin domain containing 4
Mouse - 978 7 10.21 cM Nlrp4e NLR family, pyrin domain containing 4E
Rat - - 1 q12 Nlrp4 NLR family
Previous and Unofficial Names
CLR19.5 | CT58 | NALP4 | PAN2 | PYPAF4 | cancer/testis antigen 58 | NACHT, leucine rich repeat and PYD containing 4 | NLR family, pyrin domain containing 4 | Nlrp4e | RNH2 | NLR family
Database Links
Ensembl Gene
Entrez Gene
Human Protein Atlas
Physiological Functions Comments
Involved in negative regulation of autophagy and inflammation, and embryonic development.


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How to cite this page

Clare Bryant, Tom P. Monie.
NOD-like receptor family: NLRP4. Last modified on 13/04/2018. Accessed on 19/07/2019. IUPHAR/BPS Guide to PHARMACOLOGY,