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Interleukin-22α1/20β heteromer

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Immunopharmacology Ligand target has curated data in GtoImmuPdb

Target id: 1902

Nomenclature: Interleukin-22α1/20β heteromer

Family: IL-10 receptor family

Quaternary Structure: Subunits
Interleukin 20 receptor, β subunit (Ligand-binding subunit)
Interleukin 22 receptor, α1 subunit (Ligand-binding subunit)
Natural/Endogenous Ligands Click here for help
IL-20 {Sp: Human}
IL-24 {Sp: Human}

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Agonists
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Ligand Sp. Action Value Parameter Reference
IL-20 {Sp: Human} Peptide Click here for species-specific activity table Ligand is endogenous in the given species Immunopharmacology Ligand Hs Agonist - -
IL-24 {Sp: Human} Peptide Click here for species-specific activity table Ligand is endogenous in the given species Immunopharmacology Ligand Hs Agonist - -
Immunopharmacology Comments
This is a heterodimeric receptor containing interleukin 20 receptor, β subunit (IL20RB) and interleukin 22 receptor, α1 subunit (IL22RA1). It is a receptor for interleukins 20 and 24.

How to cite this page

IL-10 receptor family: Interleukin-22α1/20β heteromer. Last modified on 06/04/2017. Accessed on 11/10/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1902.