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Target not currently curated in GtoImmuPdb
Target id: 2427
Nomenclature: ubiquitin C-terminal hydrolase L3
Gene and Protein Information ![]() |
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Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | - | 230 | 13q22.2 | UCHL3 | ubiquitin C-terminal hydrolase L3 | |
Mouse | - | 230 | 14 50.9 cM | Uchl3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | |
Rat | - | 230 | 15q21 | Uchl3 | ubiquitin C-terminal hydrolase L3 |
Previous and Unofficial Names ![]() |
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) |
Database Links ![]() |
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Specialist databases | |
MEROPS | C12.003 (Hs) |
Other databases | |
Alphafold | P15374 (Hs), Q9JKB1 (Mm) |
BRENDA | 3.4.19.12 |
CATH/Gene3D | 3.40.532.10 |
ChEMBL Target | CHEMBL6195 (Hs) |
Ensembl Gene | ENSG00000118939 (Hs), ENSMUSG00000022111 (Mm), ENSRNOG00000009530 (Rn), ENSRNOG00000065893 (Rn) |
Entrez Gene | 7347 (Hs), 50933 (Mm), 498560 (Rn) |
Human Protein Atlas | ENSG00000118939 (Hs) |
KEGG Enzyme | 3.4.19.12 |
KEGG Gene | hsa:7347 (Hs), mmu:50933 (Mm), rno:498560 (Rn) |
OMIM | 603090 (Hs) |
Pharos | P15374 (Hs) |
RefSeq Nucleotide | NM_006002 (Hs), NM_001270952 (Hs), NM_016723 (Mm), NM_001110165 (Rn) |
RefSeq Protein | NP_001257881 (Hs), NP_005993 (Hs), NP_057932 (Mm), NP_001103635 (Rn) |
UniProtKB | P15374 (Hs), Q9JKB1 (Mm) |
Wikipedia | UCHL3 (Hs) |
Enzyme Reaction ![]() |
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Download all structure-activity data for this target as a CSV file
Inhibitors | |||||||||||||||||||||||||||||||||||||||||||||||||||
Key to terms and symbols | View all chemical structures | Click column headers to sort | |||||||||||||||||||||||||||||||||||||||||||||||||
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Immuno Process Associations | ||
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C12: Ubiquitin C-terminal hydrolase: ubiquitin C-terminal hydrolase L3. Last modified on 29/01/2016. Accessed on 13/02/2025. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2427.