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Target not currently curated in GtoImmuPdb
Target id: 260
Nomenclature: GPRC5C
Family: Class C Orphans
Annotation status:
Annotated and expert reviewed. Please contact us if you can help with updates.
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Gene and Protein Information ![]() |
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class C G protein-coupled receptor | ||||||
Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | 7 | 441 | 17q25.1-q25.3 | GPRC5C | G protein-coupled receptor class C group 5 member C | 2 |
Mouse | 7 | 440 | 11 E2 | Gprc5c | G protein-coupled receptor, family C, group 5, member C | |
Rat | 7 | 441 | 10q32.2 | Gprc5c | G protein-coupled receptor, class C, group 5, member C |
Database Links ![]() |
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Ensembl Gene | ENSG00000170412 (Hs), ENSMUSG00000051043 (Mm), ENSRNOG00000003144 (Rn) |
Entrez Gene | 55890 (Hs), 70355 (Mm), 287805 (Rn) |
Human Protein Atlas | ENSG00000170412 (Hs) |
KEGG Gene | hsa:55890 (Hs), mmu:70355 (Mm), rno:287805 (Rn) |
OMIM | 605949 (Hs) |
RefSeq Nucleotide | NM_018653 (Hs), NM_147217 (Mm), NM_001191591 |
RefSeq Protein | NP_061123 (Hs), NP_671750 (Mm), NP_001178520 (Rn) |
UniProtKB | Q9NQ84 (Hs), Q8K3J9 (Mm), Q3KRC4 (Rn) |
Wikipedia | GPRC5C (Hs) |
Tissue Distribution ![]() |
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Expression Datasets ![]() |
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General Comments |
Orphan receptor. mRNA expression is induced by retinoic acid in some cell lines. |
1. Bräuner-Osborne H, Jensen AA, Sheppard PO, Brodin B, Krogsgaard-Larsen P, O'Hara P. (2001) Cloning and characterization of a human orphan family C G-protein coupled receptor GPRC5D. Biochim Biophys Acta., 1518: 237-248. [PMID:11311935]
2. Robbins MJ, Michalovich D, Hill J, Calver AR, Medhurst AD, Gloger I, Sims M, Middlemiss DN, Pangalos MN. (2000) Molecular cloning and characterization of two novel retinoic acid-inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C). Genomics, 67 (1): 8-18. [PMID:10945465]