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farnesyltransferase, CAAX box, alpha

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Target not currently curated in GtoImmuPdb

Target id: 2825

Nomenclature: farnesyltransferase, CAAX box, alpha

Abbreviated Name: FNTA

Family: 2.5.1.58 Protein farnesyltransferase

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 379 8p11.21 FNTA farnesyltransferase, CAAX box, alpha
Mouse - 377 8 14.27 cM Fnta farnesyltransferase, CAAX box, alpha
Rat - 377 16q12.4 Fnta farnesyltransferase, CAAX box, alpha
Previous and Unofficial Names Click here for help
farnesyltransferase
Database Links Click here for help
BRENDA
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
Pharos
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction Click here for help
EC Number: 2.5.1.58
Inhibitor Comments
Note that for farnesyltransferase inhibitors we map the ligand interaction to the beta subunit (FNTB), although the actual active site forms in the centre of the beta subunit overlapped by the alpha subunit.
Immuno Process Associations
Immuno Process:  Cytokine production & signalling
GO Annotations:  Associated to 1 GO processes
GO:0034097 response to cytokine ISO

How to cite this page

2.5.1.58 Protein farnesyltransferase: farnesyltransferase, CAAX box, alpha. Last modified on 13/08/2015. Accessed on 28/11/2020. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2825.