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carboxyl ester lipase

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Target not currently curated in GtoImmuPdb

Target id: 2872

Nomenclature: carboxyl ester lipase

Family: 3.1.1.- Carboxylic Ester Hydrolases

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 753 9q34.13 CEL carboxyl ester lipase
Mouse - 599 2 19.38 cM Cel carboxyl ester lipase
Rat - 612 3p12 Cel carboxyl ester lipase
Previous and Unofficial Names Click here for help
BSSL | BSDL | MODY8 | bile salt-stimulated lipase | bile salt-dependent lipase
Database Links Click here for help
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction Click here for help
EC Number:
EC Number:

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Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
compound 10f [PMID: 24556381] Small molecule or natural product Pig Inhibition 5.9 pIC50 1
pIC50 5.9 (IC50 1.33x10-6 M) [1]
compound 10l [PMID: 24556381] Small molecule or natural product Pig Inhibition 5.7 pIC50 1
pIC50 5.7 (IC50 1.98x10-6 M) [1]
Immuno Process Associations
Immuno Process:  Antigen presentation
GO Annotations:  Associated to 1 GO processes
GO:0048488 synaptic vesicle endocytosis IBA


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1. Muscia GC, Hautmann S, Buldain GY, Asís SE, Gütschow M. (2014) Synthesis and evaluation of 2-(1H-indol-3-yl)-4-phenylquinolines as inhibitors of cholesterol esterase. Bioorg Med Chem Lett, 24 (6): 1545-9. [PMID:24556381]

How to cite this page

3.1.1.- Carboxylic Ester Hydrolases: carboxyl ester lipase. Last modified on 13/08/2015. Accessed on 25/09/2021. IUPHAR/BPS Guide to PHARMACOLOGY,