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RB binding protein 9, serine hydrolase

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Target not currently curated in GtoImmuPdb

Target id: 2874

Nomenclature: RB binding protein 9, serine hydrolase

Family: 3.1.1.- Carboxylic Ester Hydrolases

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 186 20p11.23 RBBP9 RB binding protein 9, serine hydrolase
Mouse - 186 2 G1 Rbbp9 retinoblastoma binding protein 9, serine hydrolase
Rat - 186 3q41 Rbbp9 RB binding protein 9, serine hydrolase
Previous and Unofficial Names Click here for help
putative hydrolase RBBP9 | Bog | retinoblastoma binding protein 9 | retinoblastoma binding protein 9, serine hydrolase | RB binding protein 9
Database Links Click here for help
Alphafold
CATH/Gene3D
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
Pharos
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia

Download all structure-activity data for this target as a CSV file go icon to follow link

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
Ala(1-naph)-Pro-CN Small molecule or natural product Hs Inhibition 6.1 pIC50 1
pIC50 6.1 (IC50 8.8x10-7 M) [1]

References

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1. Bachovchin DA, Koblan LW, Wu W, Liu Y, Li Y, Zhao P, Woznica I, Shu Y, Lai JH, Poplawski SE et al.. (2014) A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity. Nat Chem Biol, 10 (8): 656-63. [PMID:24997602]

How to cite this page

3.1.1.- Carboxylic Ester Hydrolases: RB binding protein 9, serine hydrolase. Last modified on 13/08/2015. Accessed on 25/09/2021. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2874.