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Gene and Protein Information ![]() |
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Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | - | 466 | 1q32.1 | CHIT1 | chitinase 1 | |
Mouse | - | 464 | 1 E4 | Chit1 | chitinase 1 | |
Rat | - | 464 | 13q13 | Chit1 | chitinase 1 |
Previous and Unofficial Names ![]() |
chitinase 1 (chitotriosidase) |
Database Links ![]() |
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Alphafold | Q13231 (Hs), Q9D7Q1 (Mm) |
ChEMBL Target | CHEMBL3080 (Hs), CHEMBL4105845 (Mm) |
Ensembl Gene | ENSG00000133063 (Hs), ENSMUSG00000026450 (Mm), ENSRNOG00000028072 (Rn) |
Entrez Gene | 1118 (Hs), 71884 (Mm), 289032 (Rn) |
Human Protein Atlas | ENSG00000133063 (Hs) |
KEGG Gene | hsa:1118 (Hs), mmu:71884 (Mm), rno:289032 (Rn) |
Pharos | Q13231 (Hs) |
UniProtKB | Q13231 (Hs), Q9D7Q1 (Mm) |
Wikipedia | CHIT1 (Hs) |
Selected 3D Structures ![]() |
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Download all structure-activity data for this target as a CSV file
Inhibitors | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Key to terms and symbols | View all chemical structures | Click column headers to sort | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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View species-specific inhibitor tables |
1. Koralewski R, Dymek B, Mazur M, Sklepkiewicz P, Olejniczak S, Czestkowski W, Matyszewski K, Andryianau G, Niedziejko P, Kowalski M et al.. (2020) Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis. J Med Chem, 63 (24): 15527-15540. [PMID:33078933]
Chitinases: chitinase 1. Last modified on 16/07/2021. Accessed on 11/02/2025. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=3187.