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carnitine palmitoyltransferase 1B

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Target not currently curated in GtoImmuPdb

Target id: 3250

Nomenclature: carnitine palmitoyltransferase 1B

Family: Carnitine palmitoyltransferases

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 2 772 22q13.33 CPT1B carnitine palmitoyltransferase 1B
Mouse 2 772 15 44.89 cM Cpt1b carnitine palmitoyltransferase 1b, muscle
Rat 2 772 7q34 Cpt1b carnitine palmitoyltransferase 1B
Previous and Unofficial Names Click here for help
carnitine O-palmitoyltransferase 1B | M-CPT-1 | Carnitine O-palmitoyltransferase 1, muscle isoform
Database Links Click here for help
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
Enzyme Reaction Click here for help
EC Number:

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Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
teglicar Small molecule or natural product Click here for species-specific activity table Ligand has a PDB structure Rn Inhibition 4.4 pIC50 1
pIC50 4.4 (IC50 4.34x10-5 M) [1]
Description: Measuring the incorporation of [14C]-palmitoyl residue on carnitine in intact fresh heart mithocondria from male Sprague-Dawley rats


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1. Giannessi F, Pessotto P, Tassoni E, Chiodi P, Conti R, De Angelis F, Dell'Uomo N, Catini R, Deias R, Tinti MO et al.. (2003) Discovery of a Long-Chain Carbamoyl Aminocarnitine Derivative, a Reversible Carnitine Palmitoyltransferase Inhibitor with Antiketotic and Antidiabetic Activity. Jourmal of Medicinal Chemistry, 46 (2): 303–309. DOI: 10.1021/jm020979u

How to cite this page

Carnitine palmitoyltransferases: carnitine palmitoyltransferase 1B. Last modified on 06/02/2024. Accessed on 14/06/2024. IUPHAR/BPS Guide to PHARMACOLOGY,