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Gene and Protein Information ![]() |
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Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | 3 | 632 | Xq28 | GABRQ | gamma-aminobutyric acid type A receptor subunit theta | 1 |
Mouse | 3 | 638 | X A6 | Gabrq | gamma-aminobutyric acid (GABA) A receptor, subunit theta | 3 |
Rat | 4 | 635 | Xq37 | Gabrq | gamma-aminobutyric acid type A receptor subunit theta | 3 |
Database Links ![]() |
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CATH/Gene3D | 2.70.170.10 |
ChEMBL Target | CHEMBL3885575 (Hs), CHEMBL2094133 (Mm) |
DrugBank Target | Q9UN88 (Hs), Q9UN88 (Hs) |
Ensembl Gene | ENSG00000147402 (Hs), ENSMUSG00000031344 (Mm), ENSRNOG00000016884 (Rn) |
Entrez Gene | 55879 (Hs), 57249 (Mm), 65187 (Rn) |
Human Protein Atlas | ENSG00000147402 (Hs) |
KEGG Gene | hsa:55879 (Hs), mmu:57249 (Mm), rno:65187 (Rn) |
OMIM | 300349 (Hs) |
Pharos | Q9UN88 (Hs) |
RefSeq Nucleotide | NM_018558 (Hs), NM_020488 (Mm), NM_031733 (Rn) |
RefSeq Protein | NP_061028 (Hs), NP_065234 (Mm), NP_113921 (Rn) |
UniProtKB | Q9UN88 (Hs), Q9JLF1 (Mm) |
Wikipedia | GABRQ (Hs) |
Natural/Endogenous Ligands ![]() |
GABA |
Download all structure-activity data for this target as a CSV file
Channel Blockers | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Key to terms and symbols | View all chemical structures | Click column headers to sort | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Tissue Distribution ![]() |
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1. Bonnert TP, McKernan RM, Farrar S, le Bourdellès B, Heavens RP, Smith DW, Hewson L, Rigby MR, Sirinathsinghji DJ, Brown N, Wafford KA, Whiting PJ. (1999) theta, a novel gamma-aminobutyric acid type A receptor subunit. Proc. Natl. Acad. Sci. U.S.A., 96 (17): 9891-6. [PMID:10449790]
2. Moragues N, Ciofi P, Tramu G, Garret M. (2002) Localisation of GABA(A) receptor epsilon-subunit in cholinergic and aminergic neurones and evidence for co-distribution with the theta-subunit in rat brain. Neuroscience, 111 (3): 657-69. [PMID:12031352]
3. Sinkkonen ST, Hanna MC, Kirkness EF, Korpi ER. (2000) GABA(A) receptor epsilon and theta subunits display unusual structural variation between species and are enriched in the rat locus ceruleus. J. Neurosci., 20 (10): 3588-95. [PMID:10804200]