Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	17	1545	10q24.2	ABCC2	ATP binding cassette subfamily C member 2
Mouse	17	1543	19 36.67 cM	Abcc2	ATP-binding cassette, sub-family member 2
Rat	17	1541	1q54	Abcc2	ATP binding cassette subfamily C member 2

Previous and Unofficial Names

Canalicular multidrug resistance protein | CMOAT | cMRP | DJS | MRP2 | ATP-binding cassette, sub-family C (CFTR/MRP) member 2 | canalicular multispecific organic anion transporter | multidrug resistance associated protein 2 | multidrug resistance protein 2 | ATP-binding cassette, subfamily C (CFTR/MRP), member 2 | ATP-binding cassette

Database Links
Alphafold	Q92887 (Hs), Q8VI47 (Mm), Q63120 (Rn)
ChEMBL Target	CHEMBL5748 (Hs), CHEMBL2073681 (Mm), CHEMBL2073676 (Rn)
DrugBank Target	Q92887 (Hs)
Ensembl Gene	ENSG00000023839 (Hs), ENSMUSG00000025194 (Mm), ENSRNOG00000046727 (Rn)
Entrez Gene	1244 (Hs), 12780 (Mm), 25303 (Rn)
Human Protein Atlas	ENSG00000023839 (Hs)
KEGG Gene	hsa:1244 (Hs), mmu:12780 (Mm), rno:25303 (Rn)
OMIM	601107 (Hs)
Pharos	Q92887 (Hs)
UniProtKB	Q92887 (Hs), Q8VI47 (Mm), Q63120 (Rn)
Wikipedia	ABCC2 (Hs)

Substrates and Reaction Kinetics
Substrate Sp. Property Value Units Standard property Standard value Assay description Assay conditions Comments Reference tenofovir Hs - - 2

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference PAK-104P Hs Inhibition 5.4 pKi 1 ⤷ pKi 5.4 (Ki 3.7x10-6 M) [1]

Immuno Process Associations

Immuno Process:  Cytokine production & signalling