Top ▲
Target not currently curated in GtoImmuPdb
Target id: 782
Nomenclature: ABCC4
Abbreviated Name: MRP4
Systematic Nomenclature: ABCC4
Family: ABCC subfamily
Gene and Protein Information ![]() |
||||||
Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | 14 | 1325 | 13q32.1 | ABCC4 | ATP binding cassette subfamily C member 4 (PEL blood group) | |
Mouse | - | - | Abcc4 | ATP-binding cassette, sub-family C member 4 | ||
Rat | - | - | Abcc4 | ATP binding cassette subfamily C member 4 |
Database Links ![]() |
|
Alphafold | O15439 (Hs) |
ChEMBL Target | CHEMBL1743128 (Hs) |
Ensembl Gene | ENSG00000125257 (Hs), ENSMUSG00000032849 (Mm), ENSRNOG00000010064 (Rn) |
Entrez Gene | 10257 (Hs), 239273 (Mm), 170924 (Rn) |
Human Protein Atlas | ENSG00000125257 (Hs) |
KEGG Gene | hsa:10257 (Hs), mmu:239273 (Mm), rno:170924 (Rn) |
OMIM | 605250 (Hs) |
Pharos | O15439 (Hs) |
UniProtKB | O15439 (Hs) |
Wikipedia | ABCC4 (Hs) |
Substrates and Reaction Kinetics ![]() |
||||||||||||||||||||||||
|
Download all structure-activity data for this target as a CSV file
Inhibitors | |||||||||||||||||||||||||||||||||||||||||||||||||||
Key to terms and symbols | View all chemical structures | Click column headers to sort | |||||||||||||||||||||||||||||||||||||||||||||||||
|
1. Kalyesubula R, Perazella MA. (2011) Nephrotoxicity of HAART. AIDS Res Treat, 2011: 562790. [PMID:21860787]
2. Zelcer N, Reid G, Wielinga P, Kuil A, van der Heijden I, Schuetz JD, Borst P. (2003) Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4). Biochem J, 371 (Pt 2): 361-7. [PMID:12523936]