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Sodium-dependent HCO3- transporters C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Transporters

909
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NBCe1 (Electrogenic sodium bicarbonate cotransporter 1 / SLC4A4) C Show summary »

NBCe2 (Electrogenic sodium bicarbonate cotransporter 4 / SLC4A5) C Show summary »

Target Id 909
Nomenclature Electrogenic sodium bicarbonate cotransporter 4
Systematic nomenclature SLC4A5
Common abbreviation NBCe2
Previous and unofficial names NBC4 | electrogenic sodium bicarbonate cotransporter NBC4c | solute carrier family 4 member 5 | solute carrier family 4, sodium bicarbonate cotransporter, member 5 | solute carrier family 4 (sodium bicarbonate cotransporter), member 5 | solute carrier family 4
Genes SLC4A5 (Hs), Slc4a5 (Mm), Slc4a5 (Rn)
Ensembl ID ENSG00000188687 (Hs), ENSMUSG00000068323 (Mm), ENSRNOG00000010378 (Rn)
UniProtKB AC Q9BY07 (Hs), Q6RI88 (Rn)
Bioparadigms SLC Tables SLC4A5 (Hs)
RESOLUTE SLC4A5 (Hs)
Endogenous substrates
NaHCO3
Stoichiometry 1 Na+ : 2/3 HCO3- (out) or 1 Na+ : CO32*

NBCn1 (Electroneutral sodium bicarbonate cotransporter 1 / SLC4A7) C Show summary »

NBCn2 (Electroneutral sodium bicarbonate cotransporter 2 / SLC4A10) C Show summary »

NDCBE (NBCBE / SLC4A8) C Show summary »

BTR1 (NaBC1 / SLC4A11) C Show summary »

How to cite this family page

Database page citation:

Sodium-dependent HCO3- transporters. Accessed on 22/06/2025. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=171.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Transporters. Br J Pharmacol. 180 Suppl 2:S374-469.