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The five enzymatic steps of the Coenzyme A (CoA) synthesis pathway are highly conserved, however the amino acid sequences of the enzymes catalysing the reactions show low conservation between species.
PfPANK1 (Plasmodium falciparum pantothenate kinase 1)
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Database page citation:
Coenzyme A synthesis pathway enzymes. Accessed on 03/12/2023. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=1053.
Concise Guide to PHARMACOLOGY citation:
Alexander SP, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Introduction and Other Protein Targets. Br J Pharmacol. 178 Suppl 1:S1-S26.