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ABCA subfamily C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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To date, 12 members of the human ABCA subfamily are identified. They share a high degree of sequence conservation and have been mostly related with lipid trafficking in a wide range of body locations. Mutations in some of these genes have been described to cause severe hereditary diseases related with lipid transport, such as fatal surfactant deficiency or harlequin ichthyosis. In addition, most of them are hypothesized to participate in the subcellular sequestration of drugs, thereby being responsible for the resistance of several carcinoma cell lines against drug treatment [1-2].


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ABC1, CERP (ABCA1) C Show summary » More detailed page go icon to follow link

ABC2 (ABCA2) Show summary »

ABC3, ABCC (ABCA3) C Show summary »

ABCR (ABCA4) C Show summary »

ABCA5 C Show summary »

ABCA6 C Show summary »

ABCA7 C Show summary »

ABCA8 Show summary »

ABCA9 Show summary »

Target Id 764
Systematic nomenclature ABCA9
Previous and unofficial names ATP-binding cassette sub-family A member 9 | ATP-binding cassette, subfamily A (ABC1), member 9 | ATP-binding cassette
Genes ABCA9 (Hs), Abca9 (Mm), Abca9 (Rn)
Ensembl ID ENSG00000154258 (Hs), ENSMUSG00000041797 (Mm), ENSRNOG00000059326 (Rn)
UniProtKB AC Q8IUA7 (Hs), Q8K449 (Mm)

ABCA10 Show summary »

ABCA12 C Show summary » More detailed page go icon to follow link

ABCA13 Show summary »


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NC-IUPHAR subcommittee and family contributors

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How to cite this family page

Database page citation (select format):

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Transporters. Br J Pharmacol. 180 Suppl 2:S374-469.