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Class I transporters C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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Class I transporters are able to transport D-glucose, but not D-fructose, in the direction of the concentration gradient and may be inhibited non-selectively by phloretin and cytochalasin B. GLUT1 is the major glucose transporter in brain, placenta and erythrocytes, GLUT2 is found in the pancreas, liver and kidneys, GLUT3 is neuronal and placental, while GLUT4 is the insulin-responsive transporter found in skeletal muscle, heart and adipose tissue. GLUT14 appears to result from gene duplication of GLUT3 and is expressed in the testes [3].


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GLUT1 (Glucose transporter 1 / SLC2A1) C Show summary » More detailed page go icon to follow link

GLUT2 (Glucose transporter 2 / SLC2A2) C Show summary »

Target Id 876
Nomenclature Glucose transporter 2
Systematic nomenclature SLC2A2
Common abbreviation GLUT2
Previous and unofficial names Liver glucose transporter | GLUT2 | glucose transporter type 2, liver | GTT2 | solute carrier family 2, facilitated glucose transporter member 2 | Solute carrier family 2 A2 (glucose transporter type 2) | solute carrier family 2 (facilitated glucose transporter), member 2 | solute carrier family 2 (facilitated glucose transporter)
Genes SLC2A2 (Hs), Slc2a2 (Mm), Slc2a2 (Rn)
Ensembl ID ENSG00000163581 (Hs), ENSMUSG00000027690 (Mm), ENSRNOG00000011875 (Rn)
UniProtKB AC P11168 (Hs), P14246 (Mm), P12336 (Rn)
Bioparadigms SLC Tables SLC2A2 (Hs)
D-glucosamine (D-glucosamine > D-glucose) [2]
D-glucose (D-glucosamine > D-glucose) [2]
Labelled ligands

GLUT3 (Glucose transporter 3 / SLC2A3) C Show summary »

GLUT4 (Glucose transporter 4 / SLC2A4) C Show summary »

GLUT14 (Glucose transporter 14 / SLC2A14) C Show summary »


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How to cite this family page

Database page citation:

Class I transporters. Accessed on 06/12/2023. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters. Br J Pharmacol. 178 Suppl 1:S412-S513.