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Class I transporters C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Class I transporters are able to transport D-glucose, but not D-fructose, in the direction of the concentration gradient and may be inhibited non-selectively by phloretin and cytochalasin B. GLUT1 is the major glucose transporter in brain, placenta and erythrocytes, GLUT2 is found in the pancreas, liver and kidneys, GLUT3 is neuronal and placental, while GLUT4 is the insulin-responsive transporter found in skeletal muscle, heart and adipose tissue. GLUT14 appears to result from gene duplication of GLUT3 and is expressed in the testes [3].

Transporters

879
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GLUT1 (Glucose transporter 1 / SLC2A1) C Show summary » More detailed page go icon to follow link

GLUT2 (Glucose transporter 2 / SLC2A2) C Show summary »

GLUT3 (Glucose transporter 3 / SLC2A3) C Show summary »

GLUT4 (Glucose transporter 4 / SLC2A4) C Show summary »

GLUT14 (Glucose transporter 14 / SLC2A14) C Show summary »


Target Id 879
Nomenclature Glucose transporter 14
Systematic nomenclature SLC2A14
Common abbreviation GLUT14
Previous and unofficial names GLUT14 | SLC2A3P3 | solute carrier family 2 (facilitated glucose transporter), member 3 pseudogene 3 | solute carrier family 2 (facilitated glucose transporter), member 14
Genes SLC2A14 (Hs)
Ensembl ID ENSG00000173262 (Hs)
UniProtKB AC Q8TDB8 (Hs)
Bioparadigms SLC Tables SLC2A14 (Hs)

References

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How to cite this family page

Database page citation:

Class I transporters. Accessed on 01/12/2021. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=165.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Transporters. Br J Pharmacol. 176 Issue S1: S397-S493.