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Proton-coupled inositol transporter C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Proton-coupled inositol transporters are expressed predominantly in the brain and can be inhibited by phloretin and cytochalasin B [2].

Transporters

888
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HMIT (Proton myo-inositol cotransporter / SLC2A13) C Show summary »


Target Id 888
Nomenclature Proton myo-inositol cotransporter
Systematic nomenclature SLC2A13
Common abbreviation HMIT
Previous and unofficial names H+-myo-inositol symporter | h(+)-myo-inositol cotransporter | proton myo-inositol cotransporter | proton myo-inositol symporter | solute carrier family 2 (facilitated glucose transporter), member 13 | solute carrier family 2 (facilitated glucose transporter)
Genes SLC2A13 (Hs), Slc2a13 (Mm), Slc2a13 (Rn)
Ensembl ID ENSG00000151229 (Hs), ENSMUSG00000036298 (Mm), ENSRNOG00000015741 (Rn)
UniProtKB AC Q96QE2 (Hs), Q3UHK1 (Mm), Q921A2 (Rn)
Bioparadigms SLC Tables SLC2A13 (Hs)
Substrates
myo-inositol [2]
D-chiro-inositol [2]
muco-inositol [2]
scyllo-inositol [2]
Stoichiometry 1 H+ : 1 inositol (in) [1]

References

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How to cite this family page

Database page citation:

Proton-coupled inositol transporter. Accessed on 22/09/2021. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=167.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Transporters. Br J Pharmacol. 176 Issue S1: S397-S493.