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Mitochondrial di- and tri-carboxylic acid transporter subfamily C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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Mitochondrial di- and tri-carboxylic acid transporters are grouped on the basis of commonality of substrates and include the citrate transporter which facilitates citric acid export from the mitochondria to allow the generation of oxalacetic acid and acetyl CoA through the action of ATP:citrate lyase.


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CIC (Mitochondrial citrate transporter / SLC25A1) C Show summary »

DIC (Mitochondrial dicarboxylate transporter / SLC25A10) C Show summary »

OGC (Mitochondrial oxoglutarate carrier / SLC25A11) C Show summary »

Target Id 1053
Nomenclature Mitochondrial oxoglutarate carrier
Systematic nomenclature SLC25A11
Common abbreviation OGC
Previous and unofficial names OGC | SLC20A4 | 2-oxoglutarate carrier | mitochondrial 2-oxoglutarate/malate carrier protein | OGCP | solute carrier family 25 member 11 | 2oxoc | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 | solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11 | solute carrier family 25 (mitochondrial carrier oxoglutarate carrier)
Genes SLC25A11 (Hs), Slc25a11 (Mm), Slc25a11 (Rn)
Ensembl ID ENSG00000108528 (Hs), ENSMUSG00000014606 (Mm), ENSRNOG00000003815 (Rn)
UniProtKB AC Q02978 (Hs), Q9CR62 (Mm), P97700 (Rn)
Bioparadigms SLC Tables SLC25A11 (Hs)
malic acid
α-ketoglutaric acid
Stoichiometry Malate2- (in) : oxoglutarate2- (out)

ODC (Mitochondrial oxodicarboxylate carrier / SLC25A21) C Show summary »

SLC25A34 Show summary »

SLC25A35 Show summary »


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How to cite this family page

Database page citation:

Mitochondrial di- and tri-carboxylic acid transporter subfamily. Accessed on 17/07/2024. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Transporters. Br J Pharmacol. 180 Suppl 2:S374-469.