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Mitochondrial di- and tri-carboxylic acid transporter subfamily C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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Mitochondrial di- and tri-carboxylic acid transporters are grouped on the basis of commonality of substrates and include the citrate transporter which facilitates citric acid export from the mitochondria to allow the generation of oxalacetic acid and acetyl CoA through the action of ATP:citrate lyase.


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CIC (Mitochondrial citrate transporter / SLC25A1) C Show summary »

DIC (Mitochondrial dicarboxylate transporter / SLC25A10) C Show summary »

OGC (Mitochondrial oxoglutarate carrier / SLC25A11) C Show summary »

ODC (Mitochondrial oxodicarboxylate carrier / SLC25A21) C Show summary »

Target Id 1057
Nomenclature Mitochondrial oxodicarboxylate carrier
Systematic nomenclature SLC25A21
Common abbreviation ODC
Previous and unofficial names ODC1 | solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21 | mitochondrial 2-oxodicarboxylate carrier | oxodicarboxylate carrier | OXC | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 | solute carrier family 25 (mitochondrial oxodicarboxylate carrier)
Genes SLC25A21 (Hs), Slc25a21 (Mm), Slc25a21 (Rn)
Ensembl ID ENSG00000183032 (Hs), ENSMUSG00000035472 (Mm), ENSRNOG00000008931 (Rn)
UniProtKB AC Q9BQT8 (Hs), Q8BZ09 (Mm), Q99JD3 (Rn)
Bioparadigms SLC Tables SLC25A21 (Hs)
α-ketoglutaric acid
α-oxoadipic acid
Stoichiometry Oxoadipate (in) : oxoglutarate (out)

SLC25A34 Show summary »

SLC25A35 Show summary »

How to cite this family page

Database page citation:

Mitochondrial di- and tri-carboxylic acid transporter subfamily. Accessed on 09/12/2022. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters. Br J Pharmacol. 178 Suppl 1:S412-S513.