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Mitochondrial amino acid transporter subfamily C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Mitochondrial amino acid transporters can be subdivided on the basis of their substrates. Mitochondrial ornithine transporters play a role in the urea cycle by exchanging cytosolic ornithine (L-ornithine and D-ornithine) for mitochondrial citrulline (L-citrulline and D-citrulline) in equimolar amounts. Further members of the family include transporters of S-adenosylmethionine and carnitine.

Transporters

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solute carrier family 25 member 47 / SLC25A47 Show summary »

solute carrier family 25 member 48 / SLC25A48 Show summary »

AGC1 / SLC25A12 C Show summary »

AGC2 / SLC25A13 C Show summary »

GC2 (Mitochondrial glutamate carrier 2 / SLC25A18) C Show summary »

GC1 (Mitochondrial glutamate carrier 1 / SLC25A22) C Show summary »

ORC2 (Mitochondrial ornithine transporter 2 / SLC25A2) C Show summary »

ORC1 (Mitochondrial ornithine transporter 1  / SLC25A15) C Show summary »

CAC (Carnitine/acylcarnitine carrier / SLC25A20) C Show summary »

ORNT3 / SLC25A29 Show summary »

SLC25A38 Show summary »

CGI-69 / SLC25A39 Show summary »

MCFP / SLC25A40 Show summary »

SLC25A44 Show summary »

SLC25A45 Show summary »

Comments

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Further reading

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References

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How to cite this family page

Database page citation:

Mitochondrial amino acid transporter subfamily. Accessed on 06/12/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=204.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Transporters. Br J Pharmacol. 180 Suppl 2:S374-469.