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SLC45 family of putative sugar transporters C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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Members of the SLC45 family remain to be fully characterised. SLC45A1 was initially identified in the rat brain, particularly predominant in the hindbrain, as a proton-associated sugar transport, induced by hypercapnia [3]. The protein is predicted to have 12TM domains, with intracellular termini. The SLC45A2 gene is thought to encode a transporter protein that mediates melanin synthesis. Mutations in SLC45A2 are a cause of oculocutaneous albinism type 4 (e.g. [2]), and polymorphisms in this gene are associated with variations in skin and hair color (e.g. [1]).


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Proton-associated sugar transporter A / SLC45A1 C Show summary »

Membrane-associated transporter protein / SLC45A2 Show summary »

Target Id 1210
Nomenclature Membrane-associated transporter protein
Systematic nomenclature SLC45A2
Previous and unofficial names AIM1 | Melanin associated transporter protein (MATP) | solute carrier family 45, member 2 | blanc-sale | bls | solute carrier family 45
Genes SLC45A2 (Hs), Slc45a2 (Mm), Slc45a2 (Rn)
Ensembl ID ENSG00000164175 (Hs), ENSMUSG00000022243 (Mm), ENSRNOG00000018759 (Rn)
UniProtKB AC Q9UMX9 (Hs), P58355 (Mm)
Bioparadigms SLC Tables SLC45A2 (Hs)

Solute carrier family 45 member 3 / SLC45A3 Show summary »

Solute carrier family 45 member 4 / SLC45A4 Show summary »

Further reading

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How to cite this family page

Database page citation:

SLC45 family of putative sugar transporters. Accessed on 10/12/2023. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters. Br J Pharmacol. 178 Suppl 1:S412-S513.