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Iota subfamily C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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PKCι, PKCζ are atypical serine/threonine protein kinase C isoforms. In contrast to other PKC enzymes these are not activated by phorbolesters or diacylglycerol.

Enzymes

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PKCι (protein kinase C iota) C Show summary » More detailed page go icon to follow link

PKCζ (protein kinase C zeta) C Show summary » More detailed page go icon to follow link

References

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How to cite this family page

Database page citation:

Iota subfamily. Accessed on 14/04/2026. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=535.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Gibb AJ, Kelly E, Mathie AA, Peach CJ, Veale EL, Armstrong JF, Faccenda E, Harding SD, Southan C, Davies JA et al. (2025) The Concise Guide to PHARMACOLOGY 2025/26: Enzymes. Br J Pharmacol. 182: S307-S403.