Iota subfamily

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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PKCι, PKCζ are atypical serine/threonine protein kinase C isoforms. In contrast to other PKC enzymes these are not activated by phorbolesters or diacylglycerol.

Enzymes

PKCι (protein kinase C iota) Show summary »« Hide summary More detailed page

Target Id

1490

Nomenclature

protein kinase C iota

Common abbreviation

PKCι

Previous and unofficial names

atypical protein kinase C-lambda/iota | Pkcl | protein kinase C

Genes

PRKCI (Hs), Prkci (Mm), Prkci (Rn)

Ensembl ID

ENSG00000163558 (Hs), ENSMUSG00000037643 (Mm), ENSRNOG00000009652 (Rn)

UniProtKB AC

P41743 (Hs), Q62074 (Mm), F1M7Y5 (Rn)

EC number

2.7.11.13

Comment

Known as PKCλ in rodents

PKCζ (protein kinase C zeta) Show summary »« Hide summary More detailed page

References

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How to cite this family page

Database page citation:

Iota subfamily. Accessed on 29/11/2020. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=535.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Enzymes. Br J Pharmacol. 176 Issue S1: S297-S396.