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Tumour-associated antigens

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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This is a set of diverse proteins that have been identified as tumour antigens. They are useful tumour markers (e.g. for diagnosis and/or prognosis) and are often potential candidates for use in cancer therapy.

Targets

3212
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folate receptor alpha Show summary »


Target Id 3212
Nomenclature folate receptor alpha
Genes FOLR1 (Hs)
Ensembl ID ENSG00000110195 (Hs)
UniProtKB AC P15328 (Hs)
Antibodies
mirvetuximab soravtansine (Binding) pKd 10.1 [1]
Comment FOLR1 is expressed by some cancer cells, and is an active oncology drug target [4].

glypican 3 Show summary » More detailed page go icon to follow link

MAGE family member A3 Show summary » More detailed page go icon to follow link

trophoblast glycoprotein Show summary » More detailed page go icon to follow link

tumor associated calcium signal transducer 2 Show summary » More detailed page go icon to follow link

References

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How to cite this family page

Database page citation:

Tumour-associated antigens. Accessed on 14/06/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=904.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Buneman OP, Faccenda E, Harding SD, Spedding M, Cidlowski JA, Fabbro D, Davenport AP, Striessnig J, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Introduction and Other Protein Targets. Br J Pharmacol. 180 Suppl 2:S1-22.